Causes of Mesothelioma Disease – Symptoms and Cure

Mesothelioma is a kind of diseases that doesnt have cure yet. At its early stage, it can be managed. Mesothelioma is chiefly caused by inhaling asbestos dust.

When microscopic asbestos dust settles in the the lining of the lungs called pleura, they have the capability of causing genetic changes that create cancer cells.

Asbestos exposure is the main cause of pleural mesothelioma. Mesothelioma doctors have found many factors that raises the chance of a person’s risk of mesothelioma , but it’s not yet clear exactly how all of these factors might cause this cancer.

Risk Factors for Malignant Mesothelioma

A risk factor is anything that tends to raise your chance of getting a disease such as cancer. Different diseases have different risk factors.

Sadly, some people who get affected by the disease may have known few or no known risk factors. Mesothelioma researchers have found some factors that increase a person’s risk of mesothelioma.


Asbestos is a group of certain minerals that occur naturally as bundles of tiny fibers. These fibers can be found in soil and rocks in many parts of the world.

When asbestos dusts in the air are inhaled, they can get into the lungs. Fibers that stay in the lungs can travel to the ends of the small airways and enter the pleural lining of the lung and chest wall.

These fibers can then injure the cells of the pleura, and, over time, cause mesothelioma cancer. Asbestos dusts can also damage cells of the lung and result in asbestosis i.e. scar tissue in the lung or lung cancer.

When this disease develops as a result of asbestos exposure , it takes a long time.

In March 2009, the International Agency for Research on Cancer (IARC) reconfirmed asbestos exposure as the leading cause of mesothelioma. All forms of asbestos cause the disease.

Main Risk Factors for Mesothelioma

  • Working at an asbestos mine or asbestos-processing plant
  • Working in a high-risk occupation such as construction or heavy industry
  • Serving on military ships or facilities built with products containing asbestos
  • Living in a residential area near an asbestos mine or contaminated site
  • Disturbing asbestos products during a home renovation without proper safety measures


Zeolites are minerals which relates to asbestos chemically. An example is erionite, which is common in the rocks and soil in parts of Turkey.

High mesothelioma rates in these areas are believed to be caused by exposure to this mineral. In the United states, erionite has been detected in Nevada, Oregon, Utah, Arizona, Montana, and South Dakota. So one has to be careful!


Although the risk of mesothelioma is greater in patients who have been treated with radiation, this cancer is still rare in these patients. They have been some reports of mesotheliomas that developed after people were exposed to high doses of radiation to the chest or abdomen as treatment for another cancer.

SV40 virus

Some studies have raised the possibility that infection with simian virus 40 (SV40) might increase the risk of developing mesothelioma. But most experts agree that at this time we still don’t know if SV40 is responsible for some mesotheliomas. This important topic is still being researched.

As one grows, the risk of mesothelioma increases. Mesothelioma can occur in young people (even children), but it’s rare in people under age 45. About 2 out of 3 people with mesothelioma of the chest are 65 or older.

Mesothelioma is much more common in men than in women. This is probably because men have been more likely to work in jobs with heavy exposure to asbestos.

Gene changes
A mutation or change in the gene called BAP1 can be passed in families and has been linked to mesothelioma. But BAP1 mutations are rare.


There’s no way to completely prevent mesothelioma. But there are things you can do that might lower your risk.


Mesothelioma can be hard to treat because it typically does not grow as a single tumor mass. It tends to spread along nearby surfaces, nerves, and blood vessels.

This often makes it very hard to get rid of the cancer completely with surgery and/or radiation. For some people, palliative procedures might be used to help treat some symptoms of mesothelioma.

Because mesothelioma is a rare cancer, it has been hard for doctors to compare the value of different treatments. Only a few large clinical trials of treatments for mesothelioma have been done. In addition, many doctors have very little experience treating this disease. They usually refer patients to specialists who treat large numbers of mesothelioma patients at major medical centers.

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